When Nisha Desai and Alice Zhang met at Harvard Business School, neither of them expected that a casual conversation about their frustrations with therapy would spark the idea for something much bigger.

As they juggled graduate school and their own mental health, they often felt therapy wasn’t built for people like them – they spent more time explaining their background to their therapists than actually healing. 

They realized it wasn’t just them – there’s a gap in mental healthcare that left many in the Asian and multicultural community feeling unseen and misunderstood.

That shared realization became the seed for Anise Health: a platform built to make therapy culturally attuned, accessible, and truly effective for the AAPI community.

A Problem They Both Knew Too Well

Before their paths crossed, both founders had already seen the same issue from different directions.

Nisha, who grew up in Florida in a family of healthcare entrepreneurs, had always been drawn to questions of access and equity in care. After studying finance and marketing at the University of Pennsylvania’s Wharton School and earning her MBA from Harvard, she worked in healthcare investing and later in digital product management at Humana. It was there, while helping build a mental health app, that she started hearing a troubling pattern from thousands of users – the same barriers she had personally faced.

Nisha recalls that people weren’t saying therapy didn’t work. They were saying it didn’t fit, that they didn’t feel understood.

Alice, meanwhile, came to the same conclusion through her own deeply personal experiences. Born in China, raised across Japan and Canada, and now based in New York, she calls herself a “third culture kid.” Her multicultural background gave her adaptability, but also a sense of never fully belonging anywhere.

That feeling resurfaced when she sought therapy during business school. Despite being fluent in English, she found herself translating her own emotions for her therapist – explaining why criticism from parents felt like love, or why pursuing excellence felt non-negotiable.

Alice remembers feeling exhausted after each session, explaining her background again and again, and leaving each time feeling unseen.

Building a Culturally Grounded Model of Care

After that pivotal conversation at Harvard, the two women began mapping out what culturally attuned mental health care could look like. They spoke to clinicians, patients, payors and community leaders, testing how cultural nuance could be integrated into evidence-based therapy and coaching.

They envisioned a new kind of care model: one that didn’t require clients to educate their therapists or set aside their cultural identity at the door. Instead, therapy would start from a place of understanding.

“Alice and I really built Anise to be what we believe our community has needed during our upbringing. What we kind of wished for ourselves through our own personal journeys with therapy.”

But building what didn’t yet exist came with challenges. They had to prove — to investors, clinicians, and even the broader healthcare system — that cultural context wasn’t just a “nice to have,” but essential to effective care. Many mental health professionals hadn’t been trained to deliver culturally adaptive therapy, so Anise Health had to design that framework from the ground up: provider training programs, accurate diagnostic tools, tailored care plans, curated resources and a scalable model for personalized, culturally attuned care.

Their persistence paid off. What started as late-night brainstorming sessions between classes evolved into a fully fledged mental health platform that blends clinical rigor with cultural empathy.

Growing the Movement

Since its founding, Anise Health has facilitated over 10,000 paid appointments and built a network of 60+ licensed providers across multiple states. The company is now expanding through insurance partnerships that make culturally attuned care more affordable and accessible.

Behind the scenes, Nisha leads operations and product design, while Alice drives partnerships and provider training.

Their complementary strengths, coupled with a shared sense of purpose, have helped Anise Health raise $6.4 million in funding and gain recognition as one of the top 10 most innovative Asian Pacific-led companies to watch by NYSE, Y Combinator, and Gold House.

Redefining the Future of Mental Health for Asian Communities

For both founders, Anise Health’s success goes beyond numbers. It’s about shifting how mental health is understood and delivered, starting with a community that has long been underserved and stigmatized.

“Our goal isn’t just to make care available,” Nisha says. “It’s to make it effective, culturally relevant, and sustainable within the healthcare system.”

By creating a new gold standard of culturally attuned care, Nisha and Alice aren’t just helping Asian Americans access therapy that finally feels like it speaks their language – they’re reimagining what inclusive mental health care can look like for everyone.

Learn more about Anise Health at anisehealth.co